Hi bone buddy! I have made a decision to stop Prolia therapy based on my questionable adverse side effects. Since I have had only 2, I will take my chances I won't have an unusual fracture (i.e. thigh)...As previously mentioned I feel my bone density deterioration will be slower as I further age...I will continue walking, taking D3 and Calcium petites to maintain normal serum calcium and vitin D..I have run the gamut of both oral and IV meds to increase bone density and b to no avail..Each had awful side effects...Side effects are prevalent in all medications and since we all respond differently it can be a crap shoot.I am no doctor and am unable to advise you Peggy except see your PCP and discuss ..Normal BUN for us is 10 to 20 mg/dl and creatinine .5 to 1.1g/dl....Also, the DASH diet is beneficial...Let me know how you do Peggy....Thank you