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spiritbird2 (@spiritbird2)

Do Prolia injections affect the kidneys?

Bones, Joints & Muscles | Last Active: Apr 27 11:42pm | Replies (34)

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@hopeful33250

Hello @trinity and welcome to Mayo Connect.

I appreciate you sharing your experience with Prolia injections. I can understand your concern with the increase of PTH since the injection. Was your PTH elevated prior to beginning the Prolia treatment? Do you recall what your calcium score was? (PTH and calcium levels are usually taken at the same time).

I also have bone loss, elevated PTH and low levels of D. It all seems to work together.

You mention taking mega doses of Vitamin D. Is this the prescription strength Vitamin D or supplements that you take?

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Replies to "Hello @trinity and welcome to Mayo Connect. I appreciate you sharing your experience with Prolia injections...."

Yes, my PTH WAS ELEVATED prior to my first injection and D was very low, calcium was normal….I assumed my parathyroid was producing more in compensation…Yes, prescription strength D3…Also at that time my GFR WAS 83.5….Six months later calcium still normal, PTH STILL HIGH and GFR dropped 12 points…I am concerned about my kidney function….Every other lab is nprmal…I think prolia may be the culprit for the decrease in GFR….As for the parathyroid I am stumped…Rheumatologist plans on checking PTH AND GFR IN A FEW WEEKS. IF my results are not favorable, I may not continue with Prolia…As for the elevated PTH, TUMOR??I think more tests are needed..The b vitamin D deficiency has been ongoing…When you live in the armpit of PA where the sun doesn't shine, lol..

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