Anastazole for breast cancer and memory loss?

Posted by rosy54 @rosy54, Mar 3, 2023

Recently, my doctor stopped my Anastrozole after 5 yrs on it for breast cancer.
Since then, my memory is poor and having hard time remembering. I fear I’m developing dementia (68 yrs old) My lack of memory seems worse after stopping Anastrozole. Anyone else have similar problem?

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@rosy54

5 yrs on Anastrozole I think that’s limit on it 3 yrs usually the amount of time

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My oncologist had me on anastrazole five years. Off now one month doing fine Not as tired and no more weight gain

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@ginip

Would you share how long you were taking Anastrozole?

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5 yrs I was on anastrozole. I really never noticed memory problems while taking it. It’s now 8 yrs later and having memory issues

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@lisman1408

After about 6 months of taking Anastrozole, I couldn’t stand the memory loss any more. My husband and son made fun of me so much for my forgetfulness. My doctor switched me to Tomoxifin. I broke out in some pretty nasty hives just a few days after starting Tomoxifin. It seems I was allergic to something in it. My doctor then switched me to Exemestane and I stayed on that for about 4 years. About 6 months ago, my doctor said I could stop taking it since there was no sign of cancer returning. My memory still isn’t what I had before breast cancer. But I function just fine in my life, except for my husband often treating me like me like I have no idea what going on. He makes ‘lists’ for me so I won’t forget things. Sometimes, it’s nice to have his care, but often it’s very condescending…

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I often get “ you just asked me that” or I just told you!”
I get defensive at his remarks, he not getting it I have memory issues!

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I researched “brain fog” and “muscle and joint” side effects. I was curious what else besides estrogen being blocked from the breast to help prevent breast cancer where else was being blocked from estrogen

It turns out that the benefits of Anastrozole which I was taking actually robbed estrogen from my brain and joints/muscles.

It explained so much to me re my muscle and joint issues. I was denying my muscles and joints of something they vitally needed - estrogen!

The Brain Fog was more subtle to me until I read my research further. My basic personality had changed and I thought it was depression from my continuing and progressive joint pain. It was more than that. Realizing how the brain needed estrogen gave me additional very important considerations as I entered a 3 month hiatus from Anastrozole sanctioned by my oncologist.

The results have given me my life back on some very consequential levels. I have another month on my hiatus and will then have a much more knowledgeable conversation with my oncologist.

Bottom line here is (in my opinion) Anastrozole (that I have been taking) doesn’t CAUSE brain issues and muscle/joint issues - it INVITES them. I was told continuously that it wasn’t Anastrozole that caused the pain I was experiencing - it was arthritis.
When researched it provided the more accurate explanation -
The lack of estrogen from Anastrozole was INVITING arthritis! My knee has come back to normal and my brain to appreciate the value of focus once again.

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@reneejean

Hi Dyevooshka, thank you for your reply. I think it is important for us to let others know that we are all different and while some have negative reactions to the treatment not all of us do. There is a light at the end of the tunnel and side effects from medication can often be managed. It is a frightening diagnosis but most of us will pull through with the help of loving family and friends and a positive attitude.

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So true. PS, after a full 2 months on Anastrozole, I seem to be joining the "short term memory loss" group. Frustrating for me and annoying to my husband.(sad 😔)

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@rosy54

I often get “ you just asked me that” or I just told you!”
I get defensive at his remarks, he not getting it I have memory issues!

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You are not alone. I have joined you on Anastrozole and scattered memory.

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@ginip

I researched “brain fog” and “muscle and joint” side effects. I was curious what else besides estrogen being blocked from the breast to help prevent breast cancer where else was being blocked from estrogen

It turns out that the benefits of Anastrozole which I was taking actually robbed estrogen from my brain and joints/muscles.

It explained so much to me re my muscle and joint issues. I was denying my muscles and joints of something they vitally needed - estrogen!

The Brain Fog was more subtle to me until I read my research further. My basic personality had changed and I thought it was depression from my continuing and progressive joint pain. It was more than that. Realizing how the brain needed estrogen gave me additional very important considerations as I entered a 3 month hiatus from Anastrozole sanctioned by my oncologist.

The results have given me my life back on some very consequential levels. I have another month on my hiatus and will then have a much more knowledgeable conversation with my oncologist.

Bottom line here is (in my opinion) Anastrozole (that I have been taking) doesn’t CAUSE brain issues and muscle/joint issues - it INVITES them. I was told continuously that it wasn’t Anastrozole that caused the pain I was experiencing - it was arthritis.
When researched it provided the more accurate explanation -
The lack of estrogen from Anastrozole was INVITING arthritis! My knee has come back to normal and my brain to appreciate the value of focus once again.

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I’m waiting for results of MRI to find out once and for all what is causing my back pain. Hopefully it won’t b anything suspicious but the I’m in no man’s land at tge mo - is it side effects to Anastrozole and rivaroxaban, arthritis, or something else. I WILL change my meds irrespective of my result. I now have Breadt Cancer Nurses in Magnolia Clunic in York, on my side instead of depending on my gp surgery. So fingers crossed…. 🤞🏻🤞🏻🤞🏻🤞🏻Nothing suspicious will b found x

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@rosa1935

I’m waiting for results of MRI to find out once and for all what is causing my back pain. Hopefully it won’t b anything suspicious but the I’m in no man’s land at tge mo - is it side effects to Anastrozole and rivaroxaban, arthritis, or something else. I WILL change my meds irrespective of my result. I now have Breadt Cancer Nurses in Magnolia Clunic in York, on my side instead of depending on my gp surgery. So fingers crossed…. 🤞🏻🤞🏻🤞🏻🤞🏻Nothing suspicious will b found x

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I have my figures crossed for you too. You are doing good things for yourself!!

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@rosa1935

Hi. I have been on Anastrozole fir nearly 2 years now. I do find I’m a bit more forgetful but it’s tge pain in my back when I’m walking that’s affecting me tge most. Painkillers are not working and last Saturday I was out on an immediate release morphine tablet. I had a bad reaction to it Sunday morning so
I’m off that now. I’m thinking very strongly of giving up the Anastrozole completely. I’m 71and b4 cancer I used to walk 20-30 kilometres a week. Now I’m luckily to walk to bus stop. Can anyone help please?

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I took anastrazole for 6 weeks. It made me not feel well, always very tired, and a puffy bloated feeling in the morning. My doc had me try Exemestane. OMG! I’ve been on it for 9 days and I feel better than ever. I’m 67, have arthritis and for the last 30 years would get very tired after exercise, so did not overdo it or I’d sleep for 3 days. Yesterday I both lifted weights and did cardio, and no nap needed. No extra joint pain yet. This seems too good to be true, so the effects may change. But you might want to try it.

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@lorettalu

I took anastrazole for 6 weeks. It made me not feel well, always very tired, and a puffy bloated feeling in the morning. My doc had me try Exemestane. OMG! I’ve been on it for 9 days and I feel better than ever. I’m 67, have arthritis and for the last 30 years would get very tired after exercise, so did not overdo it or I’d sleep for 3 days. Yesterday I both lifted weights and did cardio, and no nap needed. No extra joint pain yet. This seems too good to be true, so the effects may change. But you might want to try it.

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Thank you. It’s top of my list to try. Just waiting till we get results of mri before doing any changes to meds. X

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