Are you still on Xyrem? I found it to be bad news. I had memory problems, confusion, depression, more cataplexy with injury at night than I ever had. I was on it 5 years, my brain hasn't been the same since. Even my Dr later referred to it as poison. I take Quetiapine now for sleep, it works very well. I've had narcolepsy for 37 years now. Things have gone downhill since Xyrem and I am convinced it has a lot to do with it. I just can't seem to get my brain to function the way it did pre-Xyrem.