I have been diagnosed with PV Jak 2 mutation, 2 years ago this month, started off with blood letting then moved on to Hydrea which doesn't at all agree with me. Bottom line is I am now on a reduced dose of Hydrea..3 days per week instead of 7 days & blood letting only if my HCT is over 45.. One monthly blood tests at the moment. With regard to your Jak 2 query, will leave that one to an expert to answer!
Don't know you or anyone else noticed today a message which popped up on this website which said 'Good news or something to that effect for PV sufferers!
There was a link underneath which I clicked on, it brought up a Registration option, but the drop down menu indicated that it was applicable to only to Medical Personnel! Link flew off the screen, couldn't retrieve it.
If for Medical only, due to the fact that I have that condition, I got a let down when I saw I couldn't be party to the good news! Just wonder🤔