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LDN dosing for fibromyalgia and ME/CFS

Fibromyalgia | Last Active: Oct 9 10:56am | Replies (27)

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@ripley

I started at .5mg LDN for Fibro, after one day I had increased pain so dropped down to .125mg for four days. When I increased to .250mg, I had two nights of severe insomnia, so dropped back to .125 for two days, on the second night I again had bad insomnia, so I stopped taking it two days ago. My sleep is better but I also started taking an extra 50mg Trazodone the last two nights. I've had various degrees of insomnia for 18 months, so I'm not sure if the LDN is responsible or not. I'll start again at the .125 dose soon and see how it goes. I think it helped reduce my pain a bit, so hope I can keep taking it.

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Replies to "I started at .5mg LDN for Fibro, after one day I had increased pain so dropped..."

It’s always challenging trying to untangle the side effects; hoping you find a combination that works for you.

Are you taking the LDN in the evening or morning? I had to take it in the morning because I also felt over-energized in the beginning.

HI,
I traveled to a specialist in Boston for SFN and he started me on LDN. I had researched it before that but my Primary Dr. didn't know much about it. Started with 1.5mg for 3 weeks, raised to 3.0 for 2 weeks and ending with 4.5 mg. It took a couple of months to kick in, but had a dramatic effect on mt CFS. I have a lot of pain, so for me, using it for Fibro is a waste.