Yep, if I don't want to risk those high platelet numbers, I take the medication daily, see the hematologist as needed (was down to annual, back to semi-annual due to age, I think). At 72, I've been on Anagrelide with the exception of a few months when provider changed after 10 successful years. The hyrea was NOT for me, lots of trouble stabilizing blood numbers across the board. New search brought me back to what had worked and still works. No symptoms.