I have a question about weaning off Metropoplol tartrate. I have been taking this med for approximately 6 years. It was started when I was having fluctuations of hypertension and heart palpitations. For about two years, I've been so fatigued and short of breath that I could hardly function. In the last month, it has become so bad that I can't do anything physical. My cardiologist said that I have no heart issues to cause this. I do have asthma which is pretty much controlled. I take 50 mgs of Losartan once a day, 2.5 mgs of amlodipine twice a day, and 12.5 Metropoplol tartrate twice a day. I called my cardiologist for an appointment to discus the meds with him and all I got was a call from his nurse to try discontinuing the metropoplol but to watch my blood pressure. Nothing about weaning off it but I did research and so I have just been taking 12.5 mgs once a day for 3 days. I am shaking, feel awful, blood pressure going up and down and am wondering if this is from lowering the dosage. I'm aware that I was already on a low dosage but I can be pretty sensitive to drugs. I have had problems with my blood pressure going to low and my pulse rate hardly ever goes over 50 and is sometimes in the 40's. If this continues, I will insist on an appointment and don't understand why they wouldn't give me an appointment to discuss this issue.