mogwa823: I saw your post. I just don't have any advice for you. I've been getting chemo with the 48 hour pump every 2 weeks for over a year now. I also have an HAI pump implanted in me which shoots chemo directly into my liver. It's no fun. I also had chronic diarrhea, but mine was from gall bladder surgery, not chemo. I take something called cholestryamine (sp?) which removes excess bile from my digestive tract and slows down the diarrhea. I doubt that would help you bc your diarrhea is due to chemo drugs. But I do understand how awful that chronic diarrhea is. I dealt with it for a few months after my surgery before I got the cholestryamine. My weight kept dropping and I was unbelievably weak and tired from it. You can't go anywhere or do anything. You have no energy and so you can't get any exercise. I couldn't recover from my surgery at all. (Colon resection, gall badder removal, and HAI pump implantation). I wish I had some idea that could help you. Well, there is one thing that helped me: When I cut gluten out of my diet my diarrhea slows down precipitously. I'm more of a gluten avoider than an absolute no gluten person. But when I have gotten off track and had quite a but of gluten, the diarrhea gets much worse and I have to take more doses of the cholestyramine than I had been taking previously. (I hate the stuff, so I try to take it as little as possible.) I have also noticed that I get acid reflux sometimes after I've eaten gluten. So maybe there's a chance that cutting out gluten would help you. It might be worth a shot...Many Drs pooh pooh the gluten intolerance thing, but lots of them believe it's a thing too. Good luck! I hope you find a solution. I know it's hard to go through treatment when the treatment is taking away your quality of life in big chunks. I just don't see any other way. I want to live!!! Fingers crossed that you find something that helps....