I was diagnosed with ITP in November 2011. My platelet level was 1, not 1,000, but 1. None of the staff had ever seen a living patient with low of a level before. I was in the hospital for 3 weeks being treated with mega-doses of steroids, chemo, and a trial drug N-plate before they could get my platelets at an acceptable level to go home. Once they went up, they stayed up. I had a recurrence May 2016 and was treated with steroids and IGG and again, when my platelets went up they stayed up. I decided to have spleen removed to prevent it from happening again. Well, it happened anyway with a recurrence January 2022. I was hospitalized and treated with IGG ans steroids and when I went home, Promacta, which I only was on about a week because platelets raised to an acceptable level and stayed up. (At this time the platelets are anywhere between 350,000 and 400,000). This time I was also diagnosed with hepatitis b (I'd always tested negative in the past). Since I don't use IV drugs and don't have multiple sexual partners, I'm assuming I got it from the blood treatments. Has anyone else experienced this pattern of intermittent remission ftom ITP? And does anyone know if platelets can fluctuate drastically from day to day?