@pmm Patty, your words are without a doubt, calming for many to read. @steffiney and @milo3986 please know you are not alone in any health journey. Mayo clinic connect is a very powerful platform to get support and information from! We each have our individual situations, and hearing what others experience helps us make informed decisions on our own.

When I was diagnosed with MGUS, it was a surprise. Like so many, it came from tests that showed anomalies, not ones specific for MGUS. Being an overachiever all my life, i rapidly progressed from MGUS to smoldering myeloma to multiple myeloma, but I am happy to say few of us do that. The watch and wait idea can be difficult to understand, and make us impatient, right?! But it is tried and true, and really, who wants to be on treatment before we really need to? Having a clear picture of us as a patient, we need to trust our doctors when they suggest a bone marrow biopsy to help get that definitive picture. Not everyone needs one, but most probably may at some point. I have had four now, and value the insight they brought to my complicated case.
Ginger