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Side Effects of Anastrozole - bone loss

Breast Cancer | Last Active: Jul 6, 2023 | Replies (53)

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@wpglea

I am 77 years of age,. Prior to having a lumpectomy and several lymph nodes removed a year ago June, I took myself off anastrozole because of daily migraines with auras, extreme bone ache, and a life whereby I was confined to a chair. Nine months later, doctor told me the lumps were just scar tissue. Three weeks ago I had biopsies and received another cancer diagnosis. Surgeon demands a mastectomy and 5 years of anastrozole. I must make a decision by next week. Currently I am enjoying life, which includes walking my dogs 4-5 miles a day. I should have taken the user name "Confused".

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Replies to "I am 77 years of age,. Prior to having a lumpectomy and several lymph nodes removed..."

What a nightmare! I am so sorry for your experiences. I am 78 now, it will be four years in December since surgery, so far so good. Do your research, ask lots of questions and do what you feel is best for you. One size fits all treatments aren't always the best, everyone is different.

I am so very sorry to hear of this. Perhaps having the mastectomy (and possibly staying flat) would be an appropriate course of treatment and then discuss with your oncologist along with your primary care physician, the best treatment plan when/if you should decide to continue with an aromatase inhibitor. At 77, you still have a lot of life to live. ♥️

@wpglea I had mastectomies and went "flat." I switched from generic anastrazole to brand name letrozole (Femara) and tolerated it quite well. That's just me. But it is an option to try different AI's and different manufacturers.

For bones they will offer Reclast during treatment. I have recently been offered a test dose of 20%, 1 mg vs the full 5mg. If I tolerate that, I can do a half dose, which is supposed to be just as effective. Good luck!

I am 71 and mine returned sfter 2yrs same location. I hadnt taken AI but now after mastectomy have been taking Arimidex every other day w no noticeable effects