@njed Ed – I'm going to phone "my Dave" in a little while and ask if he found my message about B6, and if so, is he in the mood to do a little neurologist-nagging? If he is, I may learn something by day's end. More and more, I can understand why so many of us surrender all control of our health care to our university-trained physicians. Doing it on your own can be mind-boggling, if simply confusing. Last evening I was studying up on B6 and B12, using literature from the NIH. What knocked me for a loop was reading how not an overabundance but a deficiency of either or both vitamins can have significant implications for a person's red blood cell count. At my last annual with my PCP, she was also knocked for a loop when reading my lab test results. She saw that, for the first time in our relationship, I was found to have a low red blood cell count or RBC. When I met with the hematologist my PCP referred me to, he drew more blood––what seemed like ten or twenty gallons but was probably a few ounces less––and concluded my low RBC was a bit of a mystery (I like to think of it as my idio-RBC, to go along with my idio-neuropathy). So, all of this studying up on B6 and B12 has got me wondering: Might I have a deficiency and not an excess of either? Or both? I think it's time to visit the lab for a new blood panel. I need fresh numbers that I can show my doctors. All of this seems to tie in nicely with the need for a patient not to rely entirely on their sharply focused specialists but to be ever-vigilant for the possibility of a common cause for an assortment of ailments. – Ray @ray666