Hello @hillrunner
Welcome to the Parkinson's support group on Mayo Connect.
I've been taking PD meds for about 15 years. I take less Carbidopa/Levodopa than you do (once a day I supplement with a Stalevo tablet), but I also have severe leg cramping. I'm really not sure if the leg cramping is caused by the medication or some other health condition or even by Parkinson's itself. It can be hard to sort out the symptoms.
If the cramping continues, it might be a good idea to run it by your PCP to see if there are any other reasons for the extreme cramping. I'm in the process of doing this myself.
As you are new to Connect, please share, as you are comfortable doing so, a bit about your diagnosis with PD. For example, how long ago were you diagnosed, what symptoms led to your diagnosis? As so many of us, struggled for years before our diagnosis, I'm wondering if it was the same for you.
I have always had occasional leg cramps, but since I was diagnosed in 2019, and started taking Sinemet, they occur with more frequency, about two times a week. I have found that by drinking a glass of water, the cramps go away. That tells me I have been dehydrated, Which may be a result of taking Sinemet. Anyhow, it is not a major concern of mine.
On the other hand, I do more frequently get a “pins and needles“ feeling in one leg, usually the left, and occasionally the right. Keeps me from getting a good night’s sleep, I never really experienced that before going on Sinemet, so I think there must be some connection between the medicine and the “pins and needles.” my neurologist told me to see an orthopedist because she felt the problem was probably caused by a pinched nerve, like my sciatic nerve.
I do not think a pinched nerve is causing my problem. I think it is more likely caused by Sinemet or the entacapone I take twice a day. I take 1.5 Sinemet tablets four times a day, or total of six tablets daily.
I am curious to see if anyone else experiences “pins and needles“ in their legs and if they have any ideas what causes it.