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Restless legs syndrome

Sleep Health | Last Active: Jul 2, 2023 | Replies (7)

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@akhw

I’ve used propranolol in the past to steady nerves before speaking.

My husband has (sadly) tried all of the agonists with the expected result. He ended up taking oxycodene as a last resort, before it was even recommended.

I’ll be asking his PCP if this is an option.

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Replies to "I’ve used propranolol in the past to steady nerves before speaking. My husband has (sadly) tried..."

Give your husband this site: https://psycnet.apa.org/record/1986-27957-001

I had 2 nights of agony with RLS. I'd used propranolol 40+ yrs earlier for public speaking too, so I knew that, at least back then, it worked for me and I didn't have side effects.

Not sure what you mean about agonists. Agonists and antagonists work on receptors of various neurotransmitters. I wandering well out of my lane here, but I'm inclined to think that my tremors and RLS were a product of an overactive sympathetic nervous system or underactive parasympathetic nervous system, so I'd be inclined to try an SNS antagonist or PNS agonist.

Anyhow, good luck to your and your husband.