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Anyone else have Symptomatic MGUS?
Blood Cancers & Disorders | Last Active: Nov 28, 2023 | Replies (73)Comment receiving replies
I read that high sugar, meat diet was associated with MGUS and high whole grains, fruits, vegetables and fish associated with lower risk. Also obesity is a known risk factor.
When I was first diagnosed and going through testing I lost over 20 lbs due to not eating/stress - I also noted the light chains dropped by about 20%.
So I am not obese but could lose 10-15 lbs as I have since gained some back. So I’m working on that - something I can control.
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Very interesting isn’t it, regarding what may or may not influence/support MGUS 🤔🙂
What diet does imho is either contribute to some sub clinical inflammatory processes based on the interaction of gut integrity and microbia (an entire topic in and of itself - there’s some very interesting research done in this area to date), or it can provide mitigation for inflammation via antioxidants and support to the gut integrity and microbia. And from what I’ve understood (keeping in mind I may or may not be correct) is that the underlying reason for and against certain foods is the propensity of that food to either contribute to or mitigate inflammatory processes in the body. From what I understand inflammation is happening as a process connected with stressors on the body, as well as general repair and maintenance as a result of wear and tear.
An interesting point regarding additional adipose tissue (and this is another topic due to the different types of adipose cells, however for now I’m generally referring to the adipose tissue that is considered to be unhealthy to have in abundance) is that it contributes to inflammatory processes, and inflammatory processes contribute to MGUS and MM: https:// www. ncbi.nlm.nih.gov/pmc/articles/PMC5653692/#:~:text=Thus%20in%20MGUS%20as%20in,pathogenesis%20of%20MGUS%20and%20MM. (Please remove spaces to activate link).
So I kind of get the feeling that there are multiple contributors to essentially a chemistry lab of inflammatory reactions in the body, and that in MGUS and MM for some reason we are having a problem with inflammation feeding into monoclonal gammopathy activity…. I need to do a bit more reading and pull a little more info together, but this is what I generally think is happening 🙂
So when it comes to diet, to ensure I get a balance of nutrients from as much ‘foodstuffs’ (not vitamin tablets) as possible, I combine known digestible sources of nutrients (eg I digest red meat very well) with anti oxidative foods that will have a protective effect while I munch on that red protein 🙌🏻🙂