I take a cranberry supplement called "Utiva" which contains 36 PAC's - the amount necessary to keep bacteria from sticking to the bladder. I also take Florastor probiotic and a prescription medication called "methenamine mandelate" which is an anti-infective medication - not an antibiotic. I take it along with 500 mg of Vitamin C. It keeps the urine acid which does not allow bacteria to grow. It is very safe and has been around for years and doctors are now starting to use it more often. Hope this helps.