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Question about PMR in addition to other autoimmune disorders?
Polymyalgia Rheumatica (PMR) | Last Active: Jun 3, 2024 | Replies (32)Comment receiving replies
I agree it is often difficult to classify rheumatologic diseases and symptoms evolve over time. The complex immune mechanism overlap and interact with our genetic makeup.
I was treated with bilateral carpal tunnel and steroid injections worked very well for me. Polymyalgia developed and prednisone again was very effective.
Remission lasted for months before new tendon and ligament inflammation
was diagnosed as psoriatic arthritis. Recent studies have found the incidence
of carpal tunnel is 40% with psoriatic arthritis.
I have found that most autoimmune inflammatory conditions will affect
multiple organ systems and can can be related to sub clinical atherosclerosis.
Make sure you are screened for cardiovascular risk.
Replies to "I agree it is often difficult to classify rheumatologic diseases and symptoms evolve over time. The..."
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Psoriatic arthritis is well represented on PMR forums. I was probably diagnosed with reactive arthritis because I didn't have psoriasis. However, people don't need to have psoriasis to have psoriatic arthritis ... go figure!
All of the spondyloarthropathies have similarities to PMR. This is what psoriatic arthritis is all about:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378889/#:~:text=Psoriatic%20arthritis%20(PsA)%20is%20an%20immune%2Dmediated%20inflammatory%20disease,the%20bowel%20(Crohn's%20disease).
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The following link compares PMR to seronegative spondyloarthropathies (SpA)
The inflammation sites for both PMR and SpA are very similar.
People diagnosed with PMR seem to experience trigger fingers and carpal tunnel problems. There seems to be inflammation in tendons and connective tissue in general when people only have PMR. I wonder what is going on since PMR is thought to be a vasculitis and is associated with GCA.
https://www.vasculitisfoundation.org/education/forms/polymyalgia-rheumatica/#:~:text=PMR%20is%20closely%20linked%20with,time%20in%20the%20same%20person.