I took Xtandi for 26 months. I did great but after 9 months off it, my PSA went from undetectable to 1.1. A PSMA PET SCAN showed the reason: a 9 mm paraortic lymph node. I was in remission for 4 years. Getting spot radiation next week. 5 sessions only. We got to be resilient. PC will not leave you alone. At least in my case. Xtandi is a great drug.