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Hashimoto's Thyroiditis and Hives

Autoimmune Diseases | Last Active: Jun 27, 2023 | Replies (22)

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@paula22

Hi, I just joined mayoclinic.org today. It is June 26th 2023
I was diagnosed with chronic urticaria about 2 years ago after starting out with a dermatologist then referred to an immunologist. He did all the scratch testing and said I was not allergic to anything. He then started me out on zolair injections 1 x a month. I get an injection in each arm. Prior to the injections my body itched all over and the hives were like scratching marks, however I wasn't scratching. Once the marks appeared I would then start to itch. I was also taking zertec once a day. Since taking the zolair injections my breakouts subsided but never have gone away. I also was prescribed hydroxine which would help somewhat, but lately my breakouts are back and I am feeling itchy all the time. I can't see my allergist until the middle of July. Could I possibly be immune to the injections? Also, prednisone didn't touch it. Is there anything else I can do at this point? Please advise and thank you for any help or resources.

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Replies to "Hi, I just joined mayoclinic.org today. It is June 26th 2023 I was diagnosed with chronic..."

You know I suddenly broke out one morning with the worst hives ever in February 2023. Huge. Long. Itching. Like crazy. Body was literally buzzing. (I am a tall cell variant thyroid cancer survivor 2012). I had recently been diagnosed with lupus by my rheumatologist. He sent my lupus labs to a special clinic in California "Exagen in Vista CA."" They ran the Avise CTD test which found the lupus. Then he ran an "alpha gal IgE panel for tick borne illness. Then "immunoglobulin E, Total" with meats, an "allergens w/comp Rflx Area 1" which was environmental, then "Food allergy profile" ALL WITH BLOOD LABS and it came back I was allergic to egg whites, wheat, soybean, and milk"!!! I am 68!!! I sort of knew about egg whites but never had an issue. I immediately cut those foods out of my diet (what a nightmare) and hives just stopped. Awhile into my new diet I started breaking out a little and when I looked more closely on the boxes guess what? They were manufactured in a plant that also processed wheat, soy, eggs etc!!!!!!!! I am so hypersensitive I can't even eat something with none of the actual ingredients but processed on the same machinery!!! I was on methyl prednisolone for awhile but found allergy pills and powder with cornstarch in it worked better so have been off steroids for a few months and doing great. Side note: I went to an allergist for skin tests and she said to me "you don't need them. Im the doctor and im very good at what I do. The hives are just urticaria!!" No. I had food allergies. Were they lupus induced ? I had no symptoms of lupus. I have no clue. But the hives are gone along with cake and cookies lol but I've also lost some much needed weight. It might be something you want to look into. But at a specialty lab like above mentioned. I had lupus labs done at a regular lab and I only showed .1 over the high on ONE test and they said they were absolutely certain I didn't have lupus. When sent to CA it came back "strongly positive" with a high number!!!! Also two mild environmental allergies. Might want to discuss with the doctor. I also have CLL leukemia (which can also present with a rash). Im glad I met this doctor. He was a godsend. Good luck to you !

@paula22 hello, I’m sure that you’re miserable because of the itching. I can’t think of anything worse. I would suggest that you try a food/allergy journal. Write down everything you eat and make a note if any itching started. Also, look at soaps including laundry soap and lotions you might use. This kind of list is helpful to the doctor.
Here is a discussion that might help. https://connect.mayoclinic.org/discussion/unexplained-itching/ The members there might have some good suggestions for you
Let me know how you get on!