Hey there Nancy1900,
Thank you; I do indeed enjoy reading research and making sense of how the puzzle of MGUS fits together.
I’ve been wondering if MGUS and other immune stem cell disorders are impacted by gut microbiology, hormones regulated by sleep, and genetic predisposition and cellular susceptibility to a plethora of environmental exposures..all over a factor of time. I’m wondering if maybe the condition is really a symptom of something else that currently isn’t known, and catching early the issues with microbes, sleep, hormones, environment, and the time a cell is exposed and the resultant changes it makes to cope would be much more effective than a passive approach to significant cellular changes that result in cellular dysfunction (ie: the current watch and wait approach) 🤔🙂
No idea what this might mean, however I do find it interesting that the ongoing search for targeted treatments get close, but then there’s sometimes another issue that is then discovered that sometimes is a barrier to the treatment being able to work across multiple variations and sub-variations; I’d like to know the why of these issues, as well as the what to do about them, and that sometimes means an inductive rather then deductive approach 🙂
Just musings of a curious mind 😉
If you do come across any research that you’d like to discuss, I would be delighted to reply to your posts and explore with you anything you find 🙂
I hope you’re having nice weather in the Pacific Northwest!
And it’s a great thing to read that having this strange, no-mans-land kind of condition isn’t as stressful for you as it used to be - I’m very pleased for you and it brings a smile to know the emotional component that often sits quite unseen beside illness is going well for you 🌺🙂
Knowing that people are coping gives hope to those who sometimes aren’t sure if it’s possible 😀
I hope you have a lovely evening 🙂