1. < Prostate Cancer

Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?

Posted by dedehans @dedehans, Aug 20, 2022

My close friend has had Pluvecto treatment suggested to him by oncologists. It is relatively new, having been approved by the FDA in March 2022. Have any of you been given this drug? I have read it is radioactive material and patient needs to stay away 6 ft from others for at least 3 days so as not to contaminate them. He has not yet decided whether to take the treatment or not as he is feeling awful enough as is.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Amanda Roe | @amandajro | Jul 3, 2023
In reply to @digger "I might be going on pluvicto depending on my test results I would like to hear..." + (show)
@digger

I might be going on pluvicto depending on my test results I would like to hear from people who have been on it and how it worked in the side effects. Thanks. Dave

Jump to this post

Hello @digger. You will notice I have moved your post on Pluvecto into an existing discussion that you can now find here:
- Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?: https://connect.mayoclinic.org/discussion/any-one-on-pluvecto-a-relatively-new-drug/

I did this to allow you to connect with members like @hbp @melcanada @stonewalker and @dwpoole.

Have you heard back on your test results?

REPLY
2 replies
dwpoole | @dwpoole | Jul 3, 2023

I have scans on July 5 which I hope show improvement.

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stonewalker | @stonewalker | Jul 3, 2023
In reply to @suwairi "What does it mean that my PSA continues to rise despite taking two doses of Pluvicto?" + (show)
@suwairi

What does it mean that my PSA continues to rise despite taking two doses of Pluvicto?

Jump to this post

My PSA also rose after two treatments. My oncologist and I decided the Pluvicto was not working and cancelled further treatments. Two weeks later my PSA plummeted from 37.6 to 7.2 and then three days later to 5.4

We're back on the Pluvicto treatment schedule.

I will say that the second dose caused me much major discomfort in my GI tract. My bowels and bladder were hard to empty for days. Managed to get past it, but I did think I was finished at that point. Depression, as we all know, is too real now.

My best wishes and prayers to all my comrades out there and their caretakers.

REPLY
2 replies
digger | @digger | Jul 10, 2023
In reply to @amandajro "Hello @digger. You will notice I have moved your post on Pluvecto into an existing discussion..." + (show)
@amandajro

Hello @digger. You will notice I have moved your post on Pluvecto into an existing discussion that you can now find here:
- Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?: https://connect.mayoclinic.org/discussion/any-one-on-pluvecto-a-relatively-new-drug/

I did this to allow you to connect with members like @hbp @melcanada @stonewalker and @dwpoole.

Have you heard back on your test results?

Jump to this post

Yes more cancer none in lymp notes ,I am able to get LU 177 I go back on chemo 7/12 I hope to only have at the most 4 cycles of chemo then on L u 177 I’m hoping currently on oxycode. For pain not looking forward to all the chemo side effects loss of taste buds don’t want to eat neuropathy in my feet but it’s better than the alternative find out more on the 12th and we go back to see the doctors to get the chemo. Thanks for asking.

REPLY
melcanada | @melcanada | Jul 11, 2023
In reply to @amandajro "Hello @digger. You will notice I have moved your post on Pluvecto into an existing discussion..." + (show)
@amandajro

Hello @digger. You will notice I have moved your post on Pluvecto into an existing discussion that you can now find here:
- Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?: https://connect.mayoclinic.org/discussion/any-one-on-pluvecto-a-relatively-new-drug/

I did this to allow you to connect with members like @hbp @melcanada @stonewalker and @dwpoole.

Have you heard back on your test results?

Jump to this post

Amanda How do I link back into Stage 4 PC tracks

REPLY
gentlemanrancher | @gentlemanrancher | Jul 12, 2023
In reply to @stonewalker "My PSA also rose after two treatments. My oncologist and I decided the Pluvicto was not..." + (show)
@stonewalker

My PSA also rose after two treatments. My oncologist and I decided the Pluvicto was not working and cancelled further treatments. Two weeks later my PSA plummeted from 37.6 to 7.2 and then three days later to 5.4

We're back on the Pluvicto treatment schedule.

I will say that the second dose caused me much major discomfort in my GI tract. My bowels and bladder were hard to empty for days. Managed to get past it, but I did think I was finished at that point. Depression, as we all know, is too real now.

My best wishes and prayers to all my comrades out there and their caretakers.

Jump to this post

For anyone plugged up... check with your doctor or pharmacist and try taking Magnesium Glycinate a couple times a day and night and it will bring fluid into your digestive tract and help you eliminate.
Also, check out herbdoc.com Intestinal formula 1 which will help your digestive muscles contract and push the goodies out.

REPLY
foamhand | @foamhand | Sep 8, 2023
In reply to @suwairi "What does it mean that my PSA continues to rise despite taking two doses of Pluvicto?" + (show)
@suwairi

What does it mean that my PSA continues to rise despite taking two doses of Pluvicto?

Jump to this post

Could be Tumor Flare. Seems MCRPC doesn't like being attacked. I will report my Pluvicto process.

REPLY
cjbbjc2010 | @cjbbjc2010 | Sep 25, 2023

Can anyone give feedback on how Pluvicto treatment response is being determined? is it MRI, CT, a PSMA PET scan with F-18 or G-68 agent? If with PSMA PET, has insurance been covering it? Cost is a concern. thanks

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