Anyone taken Evenity (romosozumab) for Osteoporosis?

I have had one infusion of 400mg Reclast a long time ago, no more. I tolerated it ok. I continued then with Alendronate I do know most important is that it has to be infused slowly. I asked for that. I had no kidney problems. You have to have your Calcium and Parathyroid measured after, that changes temporarily. One infusion improved my values in my spine a lot, so that was really positive. I had not researched this drug prior to taking it, nor, as I said earlier, did I know, that from that time forward, no dentist would want to pull a tooth anymore in my mouth, even 9 years later. Because of the dental aspect alone I would not take it again. Later, I read patients who had many infusions are the ones who seem to have significant problems.

Hi mariajean03, I am so sorry I did not answer earlier. Yes, I only had one Reclast infusion in 2014. I then continued on Fosamax for 4 more years. That worked for me. This held me for a number of years without taking further drugs. Now In 2023 my bone density has fallen to a level where I need drugs again. My research now also made me aware of how many different drugs I and other people take which contribute to bone loss. Unless you accidentally drip over it you would never know. Ps I was told by my physician, that once you are stable , the drugs in your bones will hold you for a while without needing further drugs.

@arlene7 Did you take Evenity for a year? What have been the results? I am about to start Evenity and am apprehensive. Thank you for any advice! @hopeful33250 are you aware of other discussion of Evenity? I am new to this discussion group.

Okay. I had my first Evenity injections this morning. The facility and staff were great. So far, no side effects. Not even pain or swelling at injection sites. It’s only been six hours, but I had to tell someone. 🙂

I was told about Reclast after Evenity but got a completely unacceptable response when I asked if I would be making a lifetime commitment. I was told that we could discuss this after I started the program. I got more info after mentioning making an informed decision.

What's after evenity. More meds

I had my second round of Evenity injections. Despite years of on and off fosamax both my hips and spine numbers continued to worsen. Other than a slight rash which cleared up in two days, I have had no side effects. I am very diligent about drinking lots of water and get plenty of exercise (walking, water exercise and some specific exercises for my back and shoulder). The duration of each injection is about 20 seconds and stings a bit, but I am already used to it and the nurse is very good at administering.

Prior to Evenity, fosamax for a few years, then switched to Actonel.
0ne year ‘vacation’ then Evenity.
Exploring what path looks like after Evenity. Not keen on Prolia due to loss of bone should you need to stop. Reclast?

If Reclast is used as a follow up for other meds, my doc told me that a break from meds might be possible, since it stays in the system so long. My doc will monitor what is happening, not sure how. Also Dr. McCormick suggests CTX and P1NP tests to see what is going on and anticipate the need to do more Reclast, or alendronate.
Obviously no break is possible with Prolia and I would worry about the effects of long term anti-resorption in terms of jaw and femur fractures. Our docs can inform and I also read McCormick's new book Great Bones.