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Prolia treatment for osteoporosis: What is your experience?

Osteoporosis & Bone Health | Last Active: Jul 13 3:27pm | Replies (1246)
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@hsum4

I was on Prolia for at least 8 years. The doctor wanted to transition me to Evenity, but after the 2 injections I developed really bad back pain and the injection sites swelled up. I'm not sure I want to have more bone with Evenity as it was rumored that some of the drugs that make bone cause cancer in rats. My doctor actually took an advertising ad out of his office that said one of these drugs that make bone did cause cancer in rats. He said that it wasn't a proven outcome, but it was enough to scare me away from drugs that actually make bone.
hsum

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Replies to "I was on Prolia for at least 8 years. The doctor wanted to transition me to..."
windyshores | @windyshores | Jun 19, 2023

@hsum4 Forteo and Tymlos (but not Evenity) originally had a black box warning about bone cancer, but that warning has been removed. I read that not a single human has gotten bone cancer from these medications. Of course if you have breast cancer in your bones or have had radiation, they are not appropriate. The rats in the study were given huge doses I believe.

Editing to add that Evenity does have a warning about cardiovascular risk for some patients.

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