Hi Ripley, I can take 1/2-1 4 mg. of a Tizanidine at bedtime. I am ultra sensitive to medicine and I find a 1/2 is all I need. It helps me to sleep better. It works quicker than Flexeril for me. I do not have to take it every night. The Plaquenil for lupus has been a tremendous blessing to me as well for pain. I only take 100 mg....1/2 of a 200 mg tablet as the 200 mg is too much and causes severe stomach cramping and diarrhea. I take the Plaquenil in the morning with food. I hope one of these works for you. Bless you as I know what Fibro pain is like.
Please keep me posted. Praying....