I was diagnosed with MGUS about 18 months ago (so far just high IGM and low IGA and IGG.) For the past 5 months I have become more and more fatigued and I have been checked for anemia, B12, Folate and iron. My hematologist says I should not be feeling fatigue from the MGUS at this point. I am starting to get worried because I have always walked 3-4 miles outside every day and this is not like me to feel so weak. I am having a stress/echo with a cardiologist next month but this feels more like anemia and yet my labs are OK. The fatigue is intermittent but so often now that I’m concerned. I am 69 years old, 125 lbs and have always been active and eat healthy. Anyone else with MGUS having a problem with fatigue and did your hematologist tell you the same thing? Thank you for any ideas.