← Return to Anyone take new drug Camzyos (mavacamten) for HCM?

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@nbs

I had my first echocardiogram since getting on Camzyos today and my doctor is changing my dose from the beginning 5 mg to 2.5 mg. This is my understanding as to why. Two areas they are most concerned with is the LVEF (Left ventricular ejection fraction). Mine went from 79% to 73% in the 3 1/2 weeks. They weren't concerned with this. The other area is the LVOT (Left Ventricular Outflow Tract Obstruction). Mine went from 100 mm HG to 16 mm HG. This is significant and caused the change in my prescription. The FDA does not want the LVOT to go below 20 mm HG. So, for my renewed prescription, I will go down to 2.5 mg. In four weeks I will have another echocardiogram. If my LVOT is still below 20 mm HG, I will be taken off of Camzyos and then rechecked four weeks later. If if stays at or above 20 mm HG my prescription will not change. Talk about change. I will say I haven't felt this great in years. So, let's see what happens over the month.

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Replies to "I had my first echocardiogram since getting on Camzyos today and my doctor is changing my..."

That is good information. I was also changed to 2.5. My LVOT went from 75 to 8 in the first 60 days. I started taking Camzyos March 31st. My doctor didn't say anything about staying at 20, or taking me off. I was nervous about changing to 2.5 from 5 because I was feeling so good! I am feeling good at 2.5 thankfully. I so hope I don't have to stop taking it and start feeling horrible again. I am so happy you are also feeling great! My 3rd echo is on the 19th, so we shall see...