Hello all I have mild ro21 positive and indigestion,losing weight

Pardon my ignorance, but are you talking about Sjogren's?

@abhishek80 We would love to try to help you, but we need a better explanation of your disease/disorder. Can you give us a description of why you are ro21 positive?

Ro 21 mildly postive on ana blot and had symptoms of dry mouth and eyes

Yes kind of

I had a neighbor once who had Sjogren's, and she told me it does "dry you out". I recently bumped into some information about Sjogren's that I'd not heard of before, because of some poking around the internet I was doing because of a different health problem that I have. I was trying to learn about some enzymes called aldehyde dehydrogenases. It turns out that one of them, or a weakness in one of them, has been linked to Sjogren's. The name of the enzyme is ALDH3a2, I believe. If you are interested in this sort of thing I can tell you what I've come across so far?

Are you saying that you are still waiting for a diagnosis? Waiting can be very emotionally draining!