Have you looked into the HAI pump? It pumps chemo directly into your liver and since your liver is where everything is metabolized they can pump something like 400 times the normal dose of chemo without it hurting the rest of your body; only the liver is affected. They will only do it if your colon cancer is contained to the colon and liver. It's not available everywhere. My original Drs. didn't know anything about it. MD Anderson in Houston doesn't do it, but MSK in NYC has been doing it for 15-20 years. I have recently had the pump implanted at MSK in NY. If there's some way to send me a personal msg with your phone number I would happily give you a call tell you all I know about it.