Also if I get on Embrel or Humana do I have to take forever or does RA go into remission?

@kstar077 I've had RA for 12 years. Initially Enbrel seemed like it helped, but no miracle drug. I was on it for two years and my hands and feet got worse while I was on it in the second year, and then it did an epic fail. I went into a really bad flare for about four months. I have been on Orencia since then and I feel much better than I did on anything else. It is working, but I probably need something to supplement it, yet my Dr. hasn't found anything as I'm a "complicated case" and can't take a lot of the different RA meds due to either interactions with other drugs I have to take, or other diseases I have that preclude me from using them. I also have a high RA Factor. I do have hand and foot deformities, but Orencia has slowed it down a bit and it's been good from the pain standpoint. I also don't feel like I'm being poisoned which I did on MTX. My hands are to the point where I've seen a hand surgeon who advised that I have Silicone MCP joint arthroplasty for four of my knuckles on left hand, then the right a year later. I'm weighing whether I want to or not.