I have been on Coreg CR ER 10 mg for a myocardiobridge since 2006, without incident until 2016 when the local pharmacist decided to change it to carvedilol generic Coreg, which began a whole host of adverse effects. The first began as chest pain, a squeezing type of feeling, shortness of breath, a body rash, and general malaise feeling. Tired/fatigued, and dizzy. After several months of fighting the insurance company to cover the brand, I was finally able to get back on Coreg CR extended-release 10mg without further problems until 2022 when the new company Woodward bought out Glaxo K, and began replacing the Brand Coreg CR ER with Carvedilol generic medication inside of Coreg brand packaging.
I did not notice any difference in the pills as they look identical, green and white, and the letters GSK 10 however, when compared to the Brand, they are markedly different as the Coreg brand will say Coreg on them. ( It's small but definitely different) I began to get a patterned itchy rash throughout my body with toxic levels of Neut/# K/ul, in my labs. I experienced chest pain, headaches, nausea, and edema swelling in my legs hands, and feet. I am 5'5" and 156 lbs, and not overweight, I have never had swelling in any of my extremities before. The adverse reactions to Carvedilol have left open flexural exanthema rashes that spread, disfiguring hyperpigmentation throughout my body and debilitating fatigue, and stomach problems. I have not had a good reaction to this medication, and caution anyone taking it to monitor your symptoms very carefully and report them immediately to your doctor.
The generic has the same medication but could have different inert compunds than the other. A good possibility is that you are having an allergic reaction to a non- medical compound. Talk to your doctors about teating and treating a possible allergy. You were right to go back to the higher cost brand.