Concerned about the side effects of anastrozole

Posted by tinalove @tinalove, Jan 31, 2016

I completed all treatments for breast cancer but now I am supposed to take hormone blocker, named anastrozole. im concerned about the side effects. Has anyone here taken it and did anyone have hair loss?

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@lisman1408

@francine6829 Yes, side effects on tamoxifen are very similar to those I experienced on Anastrozole; but I think I tolerate tomoxifin a little better so for now I plan to continue with it. I went to an emergency clinic and the doctor there prescribed a 7 day course of cortisone to clear up the hives and itching. I also am seeing an allergist this coming week for some further investigation of any allergies that may have developed that could cause the hives. I’d have liked to get in to the allergist sooner, but each one I called was booked out for several weeks. I truly think the hives are reaction/side effect to my cancer meds. because I stopped the Anastrozole for about a week, the hives cleared up on their own. That’s when I contacted my oncologist and she switched me from Anastrozole to Tomoxifin, but the hives returned when I started taking the tomoxifin.

The hives are/were miserable, but for me, the worst with either of these drugs, is the brain fog and memory loss. I am able to function pretty well, but the mental sharpness that I had previously just isn’t there anymore. My husband hasn’t been very kind about it either and makes fun of me because I forget things so easily. I’ve learned I need to use some coping skills to help me like writing important things down and making lists. I very grateful for technology that I can keep those lists on my tablet, and I take it everywhere with me. I’m able to continue to work part time, and my co-workers are wonderfully understanding, so that’s a great way to help keep my self esteem up.

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Lisman, are you having joint and bone pain with tamoxifen? I do not think that is one of the side effects. My biggest issue with Femura

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@francine6829

Lisman, are you having joint and bone pain with tamoxifen? I do not think that is one of the side effects. My biggest issue with Femura

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Good question! And unfortunately I have to answer with ‘I don’t know’. I was diagnosed with osteoarthritis in my shoulders and knees about 10 years ago. But now, I don’t know if the worsening of joint pain is from further deterioration from arthritis, or if it’s from the cancer drugs. My shoulders and knees seem to be worse now than what they were last year when I was diagnosed with BC. I don’t know if my joints have worsened because I couldnt keep up with much exercise following surgery and radiation, or if it’s the cancer meds that are causing increased joint pain. But, yes, my joint pain has worsened over the past year since I was diagnosed. I’m back now to my regular yoga classes and that does seem to help, whatever the cause.

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@lisman1408

@francine6829 Yes, side effects on tamoxifen are very similar to those I experienced on Anastrozole; but I think I tolerate tomoxifin a little better so for now I plan to continue with it. I went to an emergency clinic and the doctor there prescribed a 7 day course of cortisone to clear up the hives and itching. I also am seeing an allergist this coming week for some further investigation of any allergies that may have developed that could cause the hives. I’d have liked to get in to the allergist sooner, but each one I called was booked out for several weeks. I truly think the hives are reaction/side effect to my cancer meds. because I stopped the Anastrozole for about a week, the hives cleared up on their own. That’s when I contacted my oncologist and she switched me from Anastrozole to Tomoxifin, but the hives returned when I started taking the tomoxifin.

The hives are/were miserable, but for me, the worst with either of these drugs, is the brain fog and memory loss. I am able to function pretty well, but the mental sharpness that I had previously just isn’t there anymore. My husband hasn’t been very kind about it either and makes fun of me because I forget things so easily. I’ve learned I need to use some coping skills to help me like writing important things down and making lists. I very grateful for technology that I can keep those lists on my tablet, and I take it everywhere with me. I’m able to continue to work part time, and my co-workers are wonderfully understanding, so that’s a great way to help keep my self esteem up.

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Have you or anyone had the MammaPrint test done? Google it if you have not. One of my friends recommended it to me. Francine

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@francine6829

Have you or anyone had the MammaPrint test done? Google it if you have not. One of my friends recommended it to me. Francine

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Never heard of this. I see it's a genetic test. I had the oncotype test instead. They both predict the re-occurrence of the tumor. But Thanks for the info. I feel like the better we are all informed - that's only a good thing.

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@francine6829

Have you or anyone had the MammaPrint test done? Google it if you have not. One of my friends recommended it to me. Francine

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@francine6829
I had a Mammaprint done. If you talk to your oncologist, he/she will tell you that, depending on the particular characteristics of your cancer, some of these tests are not going to work for you. In my case, the OncotypeDX was not viable, but the Mammaprint was.

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Elizm, I had the oncotype (low score) which as I understand showed that chemo was not necessary. What did you learn from the Mammoprint?

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@kathyomaha55

Never heard of this. I see it's a genetic test. I had the oncotype test instead. They both predict the re-occurrence of the tumor. But Thanks for the info. I feel like the better we are all informed - that's only a good thing.

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Kathy, I had the oncotype and it was a low score which meant I did not need chemo. My understanding is that the Mammoprint is another test for reoccurence possibilities

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@elizm

@francine6829
I had a Mammaprint done. If you talk to your oncologist, he/she will tell you that, depending on the particular characteristics of your cancer, some of these tests are not going to work for you. In my case, the OncotypeDX was not viable, but the Mammaprint was.

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@elizm what is the difference? Why would one be viable vs the other? I had oncotype and my number was 19 and found the RAD51C mutation. Thus oophorectomy / hysterectomy and 20 radiation treatments

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@francine6829

Elizm, I had the oncotype (low score) which as I understand showed that chemo was not necessary. What did you learn from the Mammoprint?

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@francine6829 @kathyomaha55
It's was the MammaPrint 70-Gene Risk of Recurrence which essentially told me that I was at high risk for recurrence within 10 years without chemo and hormonal therapy. As I recall, it's the report for those who are ER+. There's a secondary report which financially is separate -- BluePrint 80-Gene Molecular Subtype -- which my oncologist did not request.

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@gwinter

@elizm what is the difference? Why would one be viable vs the other? I had oncotype and my number was 19 and found the RAD51C mutation. Thus oophorectomy / hysterectomy and 20 radiation treatments

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Gwinter. Google does a better job than me explaining the difference

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