@pkalkstein thanks for that info on your split dose. I think it was first here on the Mayo site where i discovered PMR patients describing splitting the dose. I am now taking three X 10 mg ( early morn, about 3pm and then 8:30pm) Yesterday i was seen at Urgent care because i thought i had a lyme tick bite mark (yikes !) and my thigh was "swelling"up ? I made sure the PA knew i was taking 30mg total prednisone and she asked me point blank "how are you doing with sleeping ?" (because you are taking 10 mg in evening). I said "really , insomnia right now is not the worse problem i have ! " PS - i just have a sore hamstring- i refuse to have Lyme plus PMR !