Thank you, Young,
Acutely, my treatment plan is to have chemo every two weeks, and I was experienced this painful since the first FOXFIRE (I had Eight sessions so far and six Fol fox earlier)session but was not last for more than Four days and got worst with next chemo.
FYI, I had PET Scan last week and It's showed an inflammation along the whole colon canal and I have appointment next week with colon and rectum specialist doctor for his advice.

Thank you again, Young for your help.