"IV antibiotics are tolerated much better than when taken orally and there’s usually fewer gut disruptions with IV application."
Very true. I had text-book case of C--difficile from oral Amoxicillin given to me by dentist. 7 days later I was recovered in hospital for one week. They gave me Vancomycin to cure it. I was also prescribed 10 days of Vancomycin when discharged. Since tablets are VERY VERY expensive, they gave me compound medication of Vancomycin (uses IV form I understand) - for ten days that was only $170 back in 2011. I have not taken an oral broadband antibiotic since. Afraid of return of C-difficile. I had no side effects from Vancomycin