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Does anyone else have MGUS?

Blood Cancers & Disorders | Last Active: 4 days ago | Replies (751)

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@loribmt

Hi @sissypuss Welcome to Mayo Connect. It can be pretty startling when we discover something on our charts and have no idea what it means.
MGUS~Monoclonal gammopathy of undetermined significance (MGUS) is a blood disorder that affects plasma cells in your bone marrow.
People can have this slowly developing condition for years without any symptoms. It’s usually found on a routine physical with blood work.

We have a number of members in this support group who also have MGUS and there are quite a few discussions besides this particular conversation. You can find those by simply typing MGUS in the search bar above. That will provide a listing of the different subjects associated with MGUS.
Since you’re new to the diagnosis, it can be helpful to read about your condition. To get you started I’ve posted 3 excellent sources so that you can learn more about MGUS.

https://www.healthline.com/health/how-serious-is-mgus
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https://www.mayoclinic.org/diseases-conditions/mgus/symptoms-causes/syc-20352362
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https://my.clevelandclinic.org/health/diseases/17744-monoclonal-gammopathy-of-undetermined-significance-mgus

If you found comment on your patient portal, was this through routine blood work with a primary care physician? If so, they should be following up with you for a referral to a hematologist( a blood specialist). Was this a recent test? Were you having any symptoms weakness, tingling or numbness?

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Replies to "Hi @sissypuss Welcome to Mayo Connect. It can be pretty startling when we discover something on..."

My MGUS was found through routine blood work (August 2022) Quest Lab suggested 2 more tests be done. Those produced the MGUS IgG results.
Prior to that I had high calcium (now diagnosed with hypercalcemia) and I have had numbness, tingling from my ankles down to my feet for some time prior to MGUS diagnosis. Very annoying. Otherwise, doing well, walk 2-3 miles every morning with neighbor.
@gingerw has been very helpful with her comments.