PSA - 17.1, are Lupron injections necessary?
My grandfather is 79, his PSA level is 17.1, he is NOT on any treatment currently. He is generally healthy and is not taking ANY medication. Should he be doing Lupron injections or with this level PSA not yet? I read the side effects and not sure the benefits outweigh the risk, in his case…
If not Lupron, are there any other treatment he should be on to ensure his PSA is not climbing up?
- concerned granddaughter
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This may be useful - https://www.urotoday.com/conference-highlights/aua-2023/aua-2023-prostate-cancer/144158-aua-2023-how-to-select-appropriate-candidates-in-their-70-s-for-psa-screening-and-curative-treatment-versus-observation-strategies.html?utm_source=newsletter_11620&utm_medium=email&utm_campaign=next-generation-imaging-updates-and-highlights-from-the-international-prostate-forum-at-the-aua
Well said
Life is what happens while you are busy making plans.
Is the clinical trial still open and if so can you send me the information to contact them, if not can you send tell me where to get the synopsis of the study. Thanks for your help.
Dave. Google apalutamide clinical trial. And Proteus clinical trial. These clinical trials are conducted all over the world and I am at the location of UCLA in Westwood Robert Reiter, MD is the urology department head and the head of this UCLA trial. Absolutely everything must be done at Westwood, CA at UCLA. Not even drawing blood or giving me pills X-rays etc can be done at any other location. When you goggle this you will be able to see the results of Erleada as compared with just lupron. Good luck!
Tried all the time. Only can work about 3-4 hour before I am exhausted. Gain 30 lbs. Cant sleep good. And depressed some of the time. No sex.
My PSA was 15.. had one Lupron shot at Mayo MN allowing that to work 2 months before radiation.. Lupron shrinks the target... the 20 session high radiation worked so PSA now below 1...for 4 years.. it worked for me. I
Ditto on the side effects. Add Zytiga to that and it's even a tougher go.
I've accepted all the downsides and look forward to the cessation of treatment in 10 - 16 mos. . One worry that I have is cognitive decline.
My ability to do crossword puzzles has decreased by a lot. Other signals have also started to flash. The scientific studies (articles) seem to be voicing similar conclusions. Androgen deprivation for 12 mos or more may contribute to non-reversible cognitive loss.
ANDRGREN DEPRIVATION THERAPY IN PATIENTS WITH PROSTATE CANCER.......
2022 Study by Jong Won Kim et al. Published in MENS HEALTH
JULY 2022.
Stage 4 to my L2 where they radiated 1 inch out in 2020 and put me back on Zolodex after 4 years off Jan its in L1 so they added Xtandi and Xgeva PSA down from 9.8 to 1.7 in 2 months tired sometimes Have to avoid Pomegranate and grapefruit juice and those small oranges? as they offset Xtandi
Get on these I'm 78 now Radiation on prostate 2017 so lasting 6 years they say 5+ if it continues to work
Thanks for the info. Good luck with all.