As I have said in my earlier posts, I took a 6 year break from taking medications. Prior to that I tried 4 of them with unfortunately no improvement. I changed my diet, started meditating, walking everyday, limited my alcohol intake and took ( and still do) many vitamins and supplements. What changed my mind was my mom dying after having osteoporosis and breaking her hip. Maybe due to the stress in my life, my DEXA numbers got much worse( and they had been stable) so I decided to start taking Evenity. I am hopeful that I will get some kind of benefit from taking this medication. I did a lot of researching and soul searching before starting this medication. Finding this site with all the support and education others have given has been very helpful. I have had 3 doses with minimal side effects. Your concerns are valid, I feel you need to make the decision that you will feel comfortable with.