I was diagnosed in December of this past year. Same thing, Jak2 mutation. I tried some alternative things too, but nothing helped. I reluctantly went on 500 mgs of HU 3 x a week and have been fortunate. I've had no negative side effects and my platelets are now in the normal range. If you really need the meds take them. You don't want a stoke or heart attack. Actually your numbers aren't that high, mine were in the upper 600's. My doctor tracked my platelet count for 6 months and it continued to go up. Good luck!