my hematologist and I discussed hydroxyurea but decided ideal way to go is only baby aspirin and phlebotomy, which currently is every 3-4 months, based on my hemoglobin number. They still run my other numbers, of course, but my hemo guy really only pays attention to the Hgb number- I determined that watching a mellow concert on YouTube during my phlebotomy is a good way to go so the night prior am sure to have my laptop charged and the wired headphones are always in my laptop case. A positive mental attitude is essential in all of this. Good diet, exercise, and supportive friends and family are important as well