Thank you much for your explanation. I just posted a few weeks ago, so the 2018 date must have been related to an older thread. I was just diagnosed with lupus this past July. I am 71 now. But I got celiac disease and Ulcerative colitis in my early 30s, and was also diagnosed at the time with chronic fatigue syndrome. I never recovered from the CFS; if anything it got more and more debilitating. And while the worst of the celiac spruce symptoms -- severe nausea -- was controlled with the gluten free diet, I never recovered my energy. So the past 40 years have been basically a search for ways to function. I have had positive ANA in the past, but apparently not other factors which together would have netted the lupus diagnosis. Now apparently all the required ones are present. So I guess I belong to your "category 3." I really appreciate your explanation. My physician is not very forthcoming, in spite of my questions. Hence my presence in this group. BTW, you say you are a practitioner, and am wondering what your field is. In any case, thanks again!