Yes, my husband has been prescribed various doses of ropinerole, pramipexol, levodopa etc…. He spent nearly 3 years working with a neurologist, adjusting dosages & exploring various registered drugs. I do think that he started experiencing the effects of augmentation. He also tried, unsuccessfully, gabapentin & pregabalin (Lyrica). None worked,

As an aside, I’d been prescribed oxycodone for pain associated with a T1-S1 spinal fusion. Out of sympathy, I I occasionally shared my oxy (I know it’s not condoned) & he found that it worked better than any of the drugs previously prescribed for him. (This was before the RLS Foundation published excerpts from studies & recommended opiates as opposed to drugs causing augmentation).

His doctor(s) read & researched the info from the Foundation that I provided & prescribed oxycodone for my husband. He times the hourly dosages & finds that the current prescription isn’t working well for him.

When your loved one says ‘I don’t know how many more years I have to live, but I don’t want to live this way’, it’s extremely alarming.

So, now my husband is taking an anti-depressant & it seems to be helping a bit. Next week we’ll discuss his oxy dosage, or the possibility of adding gabapentin back into the mix.

He’s under the care of a doctor who is willing to work with us to treat the symptoms. I just wish ‘we’ could discover the source of the problem & treat it.

Finally, I must say that our membership in the RLS Foundation and this Mayo sponsored forum have been invaluable finds.

My apologies for the long post. I suspect that many others have, or will take similar journeys. Maybe this will help them.