Hi there @finny4606 - Central Sensitization Syndrome, or CSS, begins in the central nervous system whereas a louder message is received in the brain. Like a loud speak or amplified signal.
Some examples I learned from Mayo Pain Rehab are:
1. it takes less to hurt
2. more things cause hurt
3. hurt lasts longer
4. fewer things help the hurt

Dr. Sletten from Jacksonville Mayo Clinic explains CSS and the science behind it in the following video:

- https://youtu.be/vJNhdnSK3WQ

I have CSS, and learned by ruling out a lot of other diagnoses that I was struggling with, but doctors could not pin point or provide answers to. For me, CSS is a chronic pain umbrella to a plethora of physical and sensory symptoms. People with fibromyalgia, neuropathies, migraines, IBS, etc... experience central sensitization. Sort of like when acute problems get fixed, but pain still lingers and docs can't figure out why or treatments become less effective.

Hope this helped answer your question about central sensitization. Please let me know if you have any other questions.