Connect
Who has taken Vraylar for Major Depression?
Just started 1.5mg last night and I’ve read a lot of post on different forums and it seems to break down 50% “it’s helpful” & 50% “it’s horrible.” I’ve taken too many drugs to mention over the last 18 years, plus tried ECT and Ketamine infusions but I can’t quiet the depression. Hoping for feedback. I’m Also on 3600mg gabapentin and 12.5mg Amitryptiline for nerve pain and 1mg Clonazepam for anxiety. I’m nervous about this drug.
Like
Helpful
HugInterested in more discussions like this? Go to the Depression & Anxiety Support Group.
Connect
@exitframeleft, I'm tagging fellow members like @kmj1967 @gary1316 @lilgrizz @sandij @summertime4 and @bustrbrwn22 who have experience with Vraylar (cariprazine) related to bi-polar.
It's been a few days since you started Vraylar. How are you doing?
@colleenyoung pretty good, so far. I take it at night and I am restless in bed. Other than that, no side effects that I can tell. I may switch to taking it in the mornings
-
Like -
Helpful -
Hug
1 ReactionI was taking it for the mixed episodes I get with bipolar II, but it turned out it was not for me. I got very sick to my stomach early on & it didn't go away.
Anti-psychotics in general were problematic for me, so I'm back to anti-epileptics.
-
Like -
Helpful -
Hug
1 Reaction@kmj1967 I hear you. side effects are deal-killers. I’ve been fortunate with most of my meds that I haven’t experienced side effects, but they haven’t helped me either, in most cases, so that isn’t a win. Right now, I have to say that the combo of Amitryptiline and Gabapentin is finally getting my nerve pain under control, but depression is a very different animal. I hope Vraylar helps me and that you find relief with your meds.
-
Like -
Helpful -
Hug
1 Reaction@colleenyoung Vraylar was not for me. Made me manic. Not good for someone with anxiety.
-
Like -
Helpful -
Hug
2 Reactions@colleenyoung Thanks for your feedback. I am a week or so into it and I'm restless and not sleeping well. I am not manic, but the restlessness borders on anxiousness. I am taking it for Major Depressive episodes, so I do hope the restlessness subsides soon as I need a good night's sleep and I don't want my anxiety to kick up. I hope you are doing well!
@exitframeleft Sounds similar to me. I was not sleeping at all and was working out at 2 or 3 in the morning, I couldn't sit still. Just not healthy for my anxiety. Hope you do better!
-
Like -
Helpful -
Hug
2 ReactionsBeen taking Vraylar about a month for MDD. 1.5mg every 3rd day as a means to boost my existing daily dose of sertraline. I have anxiety as well so I guess this was a way to manage that. It’s okay. Currently looking into changing meds again as this isn’t helping enough.
-
Like -
Helpful -
Hug
1 ReactionWondering if anyone has updates here? I’ve been on vraylar for about 2 weeks now for MDD and am experiencing what I believe to be restlessness, though not quite to the level of akathesia. I also have a weird feeling in my mouth, like my tongue is heavy and moving. Anyone have similar experience and did it get better over time?
Very restless after 6 weeks or so on it but amazing how it’s clipped my downturns off. I rarely get down for more than a few minutes now but the lack of sleep and restlessness is a bummer. Not exactly akathesia, like you said, but so much restlessness that I am on trazodone to help me sleep. I only get 3.5 -4.5 hours straight and somehow I make it through a very busy day at work. I’m pretty convinced that this drug is half speed and half whatever else is the patented part.