Hello @rayofhope I love your @name. It’s important to always have hope. Believe me I understand the fear that hits when there is a diagnosis of a blood cancer. I had a very aggressive form of leukemia 4 years ago and now I’m healthy, active and in a durable remission. So don’t ever give up hope with your wife’s new diagnosis.

The earliest stage of myeloma isn’t labeled as a cancer. It’s a benign condition called monoclonal gammopathy of undetermined significance. MGUS. But it can change over time and develop into Multiple Myeloma. Two years isn’t an unreasonable time for this condition to progress. For some people it can take years or maybe even never progress to the point of needing treatment. But each person is different and as cells change, the staging of the disease can change. I’m posting several links you might find helpful that explains Mgus, Smoldering Multiple Myeloma and Multiple Myeloma
This article is from Myeloma.org https://www.myeloma.org/what-are-mgus-smm-mm
Another article from Cancer.gov explains the progression risk of MGUS to MM
https://www.cancer.gov/news-events/cancer-currents-blog/2019/mgus-multiple-myeloma-progression-risk
We have a number of discussions in our Connect Blood Cancer support group with members who have Multiple Myeloma such as @gingerw @pmm
@dick12, @mitten, @whitepine66 and many others. This would be a good place for you to begin sharing in their experiences.

– Multiple Myeloma https://connect.mayoclinic.org/discussion/multiple-myeloma-26f521/

My suggestion is to not dwell on the past, on wether this could have been diagnosed sooner or not. These conditions can develop quickly as in my case, even though I had been having regular checkups.
Has your wife started any treatments?