Anyone taken Evenity (romosozumab) for Osteoporosis?

After 8 injections I decided ( at recommendation of my endocrinologist) to take a month or 2 off to see if the symptoms I was having resolve.
I developed a chronic cold with cough (had to use my inhaler) and itchy scalp w rash like bumps around my ears… very minor but noticeable to me.
So far, those are resolving interestingly. And thankfully!
So will probably stop Evenity and switch to something to keep the gains.
Thinking Reclast -
What has been everyone’s experiences ?

Hello
I was wondering if you had stopped the Evenity and switched to Reclast? How did the transition go? Did you have any side effects?

My cough is still present, less intense and it is now 25 days since my last Evenity shots. I canceled #8 round for now until I complete the ENT consult. I had a repeat DEXA with no change to scores at the hip or head of femur (but no additional loss either). I have had some improvement in scores to my spine.
Any information on the switch to Reclast would be helpful.

Thanks so much

I'm so sorry about the Covid. Strange timing.
Good to hear that the Reclast side effects were manageable and that now you're feeling better. Once my cough subsides, I hope to switch to Reclast as well.
I'll let you know what happens.
Best to you!!

I stopped after 8 months then did Reclast 3 months ago. My repeat dexascan shows 40% improvement in my lumbar spine. Going from T score of 4.0 to 2.7 for total lumbar spine.
Hips improved almost as much but they are still barely osteopenia.
So very encouraging!!

My Mom started Evenity shots November 2020. She is 84 and has "horrible" bones. Just prior to starting Evenity, she had numerous fractures. Although the side effects scare me, we felt we did not have a choice but to start her on the medication. She had Prolia shots for years, apparently it was not doing the trick. She's always drank lots of milk, takes calcium supplements, magnesium and D3. We knew we had to do something different or she would continue to have fractures. After 3 months it seems to be helping. She fell three weeks ago and did NOT fracture any bones. So far, she does not appear to have any major side effects. We pray that continues.

And to you! This forum has been so helpful as the doctors don’t seem very aware of any reactions except the initial APR (acute phase reaction) listed by the manufacturer.
I am leery of another dose though- definitely want to wait 18-24 months. I will see what the scan shows then.

Was your rash filled with liquid? I got a bad rash on my forearm with Fosamax after 3 weeks so I switched to Evenity. I’d like to follow up Evenity with a short dose of Reclast but my endo is afraid I’m allergic to bisphosphonates.

Good afternoon @dmanduca......I was looking for another diagnosis when I found your message to @kolika about an allergic reaction to bisphosphonates. So I wanted to share a bit of history with you. My PCP started me on Bonniva, also a bisphosphonate. My reaction was painful and immediate and the medication was eliminated. We replaced it with Tymlos and everything was fine for two years. To avoid another bisphosphonate reaction, my endocrinologist recommended Prolia as the only safe route with two injections a year. Within weeks, the pain in my jaw and my joints was back again.

At this point, I requested a consult at Mayo Clinic. After discussion and record review, my Mayo endocrinologist wanted me to start Alendronate. I was surprised because that medication is also a bisphosphonate. However, what he figured out and shared with me was that the twice-a-year major injections don't work for me. It is way too much medication rolling around in my body for six months. The Alendronate is available in weekly tablets. I take one every Monday morning......and then sit quietly for 30 minutes without any other food or medication. The result has been amazingly perfect. No side effects, no reactions and I have found a renewed appreciation for the thoroughness of a great clinician.
Just thought I would let you know. Is your prescribing clinician at Mayo Clinic?

May you be safe, protected and free from inner and outer harm.
Chris

Good afternoon @dmanduca......I was looking for another diagnosis when I found your message to @kolika about an allergic reaction to bisphosphonates. So I wanted to share a bit of history with you. My PCP started me on Bonniva, also a bisphosphonate. My reaction was painful and immediate and the medication was eliminated. We replaced it with Tymlos and everything was fine for two years. To avoid another bisphosphonate reaction, my endocrinologist recommended Prolia as the only safe route with two injections a year. Within weeks, the pain in my jaw and my joints was back again.

At this point, I requested a consult at Mayo Clinic. After discussion and record review, my Mayo endocrinologist wanted me to start Alendronate. I was surprised because that medication is also a bisphosphonate. However, what he figured out and shared with me was that the twice-a-year major injections don't work for me. It is way too much medication rolling around in my body for six months. The Alendronate is available in weekly tablets. I take one every Monday morning......and then sit quietly for 30 minutes without any other food or medication. The result has been amazingly perfect. No side effects, no reactions and I have found a renewed appreciation for the thoroughness of a great clinician.
Just thought I would let you know. Is your prescribing clinician at Mayo Clinic?

May you be safe, protected and free from inner and outer harm.
Chris