Humira worked GREAT for me! I was on it for a couple of years before it lost effectiveness for me. I don't remember there being any significant side effects.

There are lots of good, new medications. At this point, though, there's still a lot of trial and error needed to find the ones that work best for you.

One dose of methotrexate gave me "the runs" for a month! But it does work for some people.

Good luck with it!