Thank you for your honest and thoughtful reply. I am 60 and I have a history of breast cancer in my family and pancreatic cancer and being monitored si bio identicals are out or I would do in a heartbeat.

With low blood pressure and allergy to sulfa the blood pressure meds are not good option.

Also kidney issues which are non starter for a lot of these meds. Which is why I am asking bc I have a lot to navigate. I think my concern is also yes - the first few months or year or two the Gail is there but doesn’t stay and requires further meds and in the longer term is when the atypical femur fractures happen as do other complications - I am trying to get comfortable with the risks and long term effects. It’s possible I could do great on these. Issue is that I have taken meds before where drs say it’s okay and have had very bad side effects some long lasting and I am also navigating the trade off.

I would love to hear how people are doing 5 or more years down the line as I know this is not a one and done type of thing.

Thank you again for your response. It is very helpful.