Post surgery with several lymph nodes positive went on Lupron for 15+ years.
Hot flashes resolved quickly and good control of PSA until eventual bony metastasis and switched to zoladex.
Many ongoing treatments, chemo, hormones radioactive radium and will start lutetium.
What was discovered about lupron, and other ADH treatments I suppose, is the occurrence of coronary artery disease which resulted in CAD and bypass surgery in a guy with no risks for CAD: low cholesterol, high HDL cholesterol and 4-6 hours/week of vigorous exercise:running, tennis, hiking ……
Control risk factors and talk to doc about Lupron and risk of heart disease. It’s real but I was/am on ADH treatment for 20 years and still alive.
The other inevitable is loss of muscle mass which is very significant. Good question for doc.