It is my understanding and I may be off a bit, that Xtandi and Erleada are both very expensive drugs that are androgen receptors inhibitors. I was on Erleada and lupron in a Jansen Clinical trial at UCLA. Xtandi and Erleada both work in the same fashion, are about equally effective, have the same side effects and compliment drugs such as Lupron, the standard ADT, the hormone deprivation treatment. CRPC, such as my cancer, (castration resistant prostate cancer) is resistant to the full effect of lupron, ADT treatment, and Xtandi and Erleada were developed to kill more androgens that evade standard ADT. The side effect of lupron and Erleada were certainly noticeable for me but tolerable and considering the good that they do, I was pleased to get this treatment. If my PSA goes up I will probably be back on these drugs but I am hoping that my PSA is very stable for a very long time. I hope for a good result with few side effects for you and me and all of the guys on this site.